Bio-modification approach for novel dentine caries management by Galla chinesis extract and microbial transglutaminase
نویسندگان
چکیده
منابع مشابه
Microbial biotransformation—A novel approach for modification on coumarin substrates
Microbial biotransformation, one of the tools of green chemistry, is widely used in organic synthesis to cutshort number of organic intermediates in obtaining the final required compounds. In the present study, an approach was made for preparing substituted derivatives of coumarin as therapeutic agents. Nine biotransformation experiments were performed where random combination of four microorga...
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Microbial transglutaminase, which could catalyze the cross-linking of many proteins or non-protein materials, has been widely used in food, pharmaceutical and textile industry. To enhance the yield of the enzyme and establish corresponding platform for molecular modification, the researchers of Japanese Ajinomoto began to construct the recombinant strain producing transglutaminase in the 1990s....
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The number of new technologies emerging each year in the realm of dental caries management is growing at an exponential rate. Examining the patent literature, one can see that this growth rate will likely continue, with the outcome that dentistry will see an expanded growth in managing dental caries by risk assessment with medicinal therapeutic interventions. Restorative dentistry solutions, tr...
متن کاملFluorescent substrates for covalent protein labeling catalyzed by microbial transglutaminase.
Novel small substrates with a variety of fluorophores were designed for the covalent labeling of proteins catalyzed by microbial transglutaminase (MTG). The new design is based on the flexibility in the substrate recognition of MTG for the substitution of the N-terminal protecting group of a conventional transglutaminase substrate, benzyloxycarbonyl-L-glutaminylglycine (Z-QG). Here we report fo...
متن کاملCharacterization of microbial transglutaminase
A “ready-to-use” preparation for the production of frankfurter type sausage („Activa WM“, AJINOMOTO Europe Sales GmbH, Hamburg) was used for the studies. Protein was determined by a modified method according to Bradford [1]. Results were calculated using the absorbance quotient of A590nm and A450nm. SDS polyacrylamide gel electrophoresis (SDS-PAGE) was carried out according to Laemmli [2] on a ...
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ژورنال
عنوان ژورنال: Dental Hypotheses
سال: 2012
ISSN: 2155-8213
DOI: 10.4103/2155-8213.106835